Download e-book for kindle: A Computer Scientist's Guide to Cell Biology: A travelogue by William W. Cohen

By William W. Cohen

This functional advisor offers a succinct therapy of the overall options of cellphone biology, furnishing the pc scientist with the instruments essential to learn and comprehend present literature within the field.

The booklet explores 3 varied features of biology: biological platforms, experimental methods, and language and nomenclature. After a quick creation to phone biology, the textual content makes a speciality of the rules at the back of the most-widely used experimental tactics and mechanisms, bearing on them to well-understood innovations in machine technological know-how.

The presentation of the fabric has been ready for the reader’s fast grab of the subject: reviews on nomenclature and history notes may be ascertained at a look, and crucial vocabulary is boldfaced in the course of the textual content for simple identification.

Computer technological know-how researchers, execs and desktop technology scholars will locate this an incomparable source and a very good place to begin for a extra finished exam of mobilephone biology.

"This concise booklet is a superb creation for laptop scientists to the interesting revolution below means in molecular biology. It presents lucid, high-level descriptions of the elemental molecular mechanisms of existence, and discusses the computational ideas concerned. I want this little gem used to be to be had while i used to be ‘learning the ropes’– it is going to were my first number of examining material."

--Roni Rosenfeld, Carnegie Mellon University

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Extra resources for A Computer Scientist's Guide to Cell Biology: A travelogue from a stranger in a strange land

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Good confocal microscopes can produce 3D images that include information from many different dyes. The confocal microscope was patented by Marvin Minsky (one of the founders of artificial intelligence) in 1957, but only became practical years later, with the development of lasers. Electron microscopes Electron microscopes use higher-fre- Mitochondria are organelles quency wavelengths, which gives them that produce energy from improved resolution, relative to optical glucose and oxygen. Actin is microscopes.

Gene chips and microarrays are new technology, but not a new technique: they are essentially just high-resolution versions of Northern and Southern blots. There is also a high-resolution analog of the Western blot, called a proteome chip in which many proteins are attached to a single chip—perhaps a transcription of every yeast gene—and which can be manufactured reliably2. The proteome chip is a more recent Table 2. Methods for selecting components of mixture that satisfy some property. g. of proteins Does a mixture component bind to a user-selected substance?

High-energy state. The most common of This reaction is called these “fuel” molecules is adenosine, hydrolysis. which can be found in two forms in the cell: adenosine triphosphate (ATP), the higher-energy form, and adenosine diphosphate (ADP), the lower-energy form. Enzymes are the means by which this energy is harnessed. Usually this is done by coupling some reaction PÆQ that requires energy with a reaction like ATPÆADP, which releases energy. If you visualize the potential energy in a molecule as vertical position, you might think of this sort of enzyme as a sort of see-saw, in which one molecule’s energy is increased, and another’s is decreased, as in the figure below.

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